THE PURE EP™ PLATFORM

Cardiac Signal Insights with Unprecedented Clarity and Precision

Cardiac Signal Insights with Unprecedented Clarity and Precision

PURE EP™ reveals unprecedented levels of signal clarity, providing advanced visualization of critical physiologic information for intracardiac signals — even the most complex.

Displaying results of signals from Pure EP compared to conventional products

PURE EP™’s Algorithmic Noth (AN) can eliminate environmental noise without harmonic ringing. Conventional classic notch (CN) creates artifact and signal attenuation, introducing false and misleading physiologic fractionation.

Full-Spectrum Intracardiac Signal Insights with Proprietary Technology

Noise Reducing Technology

Noise Reducing Technology

Acquire raw intracardiac signal information without distortion and view cardiac signals in their pure, original format.

Signal Data Preservation

Signal Data Preservation

Dynamic analysis allows for full-spectrum signal evaluation while highlighting and retaining a new level of signal specificity.

Wide Signal Capture

Wide Signal Capture

Detect the smallest signals without the need to gain switch, for clearer and more accurate visualization of both small and large signals.

Trusted Unipolar Data

Trusted Unipolar Data

Finally gain access to reliable unipolar data, with a cutting-edge signal pathway that emulates bipolar data acquisition.

Enhanced Visualization

Enhanced Visualization

A large frequency bandwidth 
 preserves intracardiac signals 
 within the cardiac window.

Clearly View the Cardiac Window of Interest

PURE EP™ reveals a never-before-seen view of the cardiac window of interest1 — the PURE ZONE™ — including critical signals at high frequency and low amplitude.

Conventional Signal Acquisition

Conventional Signal Acquisition chart diagram

PURE EP™ Signal Acquisition

PURE EP™ Signal Acquisition chart diagram

Access the Full Value of Unipolar Signals

PURE EP™ delivers clear, stable, and trusted unipolar data.

Time Savings icon TIME SAVINGS

Reduction in RF time, from the 24 seconds required to achieve the ablation index (AI) target, down to 8 seconds with the unique PURE EP™ unipolar signal capabilities.2

Case Efficiency icon CASE EFFICIENCY

Demonstrated improvement in case efficiency with optimized focal and linear RF workflows when using PURE EP™ during unipolar guided lesion assessment.2,3,4

1. Edzards, M., et al. (2019, December). Frequency bandwidth comparative testing using a novel signal processing platform in a controlled bench top setting. ©BioSig Technologies, Inc. Rev A2.1.01 2020[27].
2. Tabaja, C., et al. (2023, May). PO-01-200 Unipolar Signal Modification-Guided Radiofrequency Ablation. [Abstract]. Heart Rhythm 2023, New Orleans, LA. 20(5): S187. DOI: https://doi.org/10.1016/j.hrthm.2023.03.576.
3. Tanaka-Esposito, C., et al. (2023, May). PO-03-037 Feasibility of Unipolar Signal Guided Ablation in Creating Contiguous Lines of Conduction Block: A Proof-of-Concept Study [Abstract]. Heart Rhythm 2023, New Orleans, LA. 20(5): S448-S449. DOI: https://doi.org/10.1016/j.hrthm.2023.03.985.
4. Yavin, H., et al. (2023, May). PO-02-002 Comparison of Unipolar Electrogram Monitoring during Radiofrequency Ablation in Viable and Ablated Myocardium: Loss of the S-component [Abstract]. Heart Rhythm 2023, New Orleans, LA. 20(5): S324-325. DOI: https://doi.org/10.1016/j.hrthm.2023.03.762.

Proprietary Software-Based Features

Delivering configurable features, unique algorithms and signal hygiene applications, PURE EP™ offers the freedom to explore relevant signal data for highly tailored, efficient procedures.

High Frequency algorithm (HFA)

By focusing on signals above 200Hz, the High Frequency Algorithm (HFA) adds visibility to cardiac frequency data and dynamically eliminates RF frequencies to retain clear focus on the signals targeted for ablation.

HFA demonstrated 100% specificity of near field potentials with peak-to-peak voltages of <0.1mV.5

5. Ahmed A, et al. (2023, March). ROLE OF HIGH FREQUENCY ALGORITHM OF PURE EP FOR LOW AMPLITUDE SIGNAL DETECTION DURING CARDIAC ABLATION. Journal of American Cardiology. (8_Supplement) 184. DOI: https://doi.org/10.1016/S0735-1097(23)00628-9.

Automatic Tachycardia Characterization (ATC)

Subtle changes in complex tachycardias can be difficult to detect with the naked eye. Automatic Tachycardia Characterization (ATC) swiftly monitors tachycardia rates and conduction patterns in real-time, alerting changes that may warrant further evaluation.

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Without ATC Activated

Without ATC Activated

ATC Activated

ATC Activated

Near Field Tracking (NFT)

Near Field Tracking (NFT) lets you track the reduction in the negative component of a unipolar intracardiac signal during ablation. Presenting a visual indication, NFT offers an automated queue when the loss of the negative component has been identified after three consecutive beats.

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Near Field Tracking (NFT)
Bringing It All Together

Bringing It All Together

PURE EP™ completes the infrastructure of the EP lab, integrating with existing technologies to streamline clinical workflows. Explore cases, presentations, and papers for firsthand physician accounts.

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